Tag Archives: HIV

Unveiling the identity of a “super-immune stimulatory” DNA

It has long been known that recognition of microbial DNA in the cytosol induces an antiviral type I interferon immune response. However, until recently, only long double-stranded DNA had been considered as immune stimulatory. Thus, it has remained unclear whether other structural features than base paired DNA stretches are crucial for activation of cytosolic DNA sensors, and if for example single-stranded reverse transcripts of lentiviruses … Continue reading Unveiling the identity of a “super-immune stimulatory” DNA »