Tag Archives: NLRP3

Hard Science

Now on stage: NLRP3 and the molecular mechanisms behind atherosclerosis

The blog goes multimedia: with their film “What is NLRP3 and why do we care?” four PhD students from the Institute of Innate Immunity (Bonn) feature what their research is about. The research group around Prof. Eicke Latz wants to understand the cellular and molecular mechanisms behind diseases like atherosclerosis, gout or Alzheimer´s disease. In all of these diseases the protein NLRP3 (NACHT, LRR and … Continue reading Now on stage: NLRP3 and the molecular mechanisms behind atherosclerosis »

Hard Science

A “Natural Killer’s“ Memory – Lifting the veil on memory cells developed by the innate immune system

For a very long period of time scientists focused on the adaptive immune system when looking for evidence of cells reacting towards a certain molecule or another specific stimulus. Today it is common knowledge that the adaptive immune system generates long-lived memory T cells that protect us from viral infection, the spread of mutated cells and invading pathogens. In contrast, Natural Killer (NK) cells were … Continue reading A “Natural Killer’s“ Memory – Lifting the veil on memory cells developed by the innate immune system »

Short Profile

Juan Francisco Rodríguez Alcázar – Understanding the signals underlying inflammation

Juan Francisco Rodríguez Alcázar is one of the new IITB students and has just started his PhD in the group of Prof. Eicke Latz (Institute of Innate Immunity) in December last year. He studied Biochemistry and Biotechnology in Spain and worked in other innate immunology laboratories before coming to Bonn.   Juan, can you summarize for us in one sentence what your PhD project is … Continue reading Juan Francisco Rodríguez Alcázar – Understanding the signals underlying inflammation »